ORNIMIX Clone B1+H120

Special warnings:

Use usual aseptic measures during all procedures related to the product administration.

The vaccination virus of avian Newcastle disease, strain Bio 52: NDV B, and the vaccination virus of avian infectious bronchitis, strain Bio 53: IBV H120, reproduce and proliferate in the organism of vaccinated chickens after application. Several days after vaccination, the vaccination viruses are excreted into the environment to a limited extent, where they can attack other sensitive animals. The safety studies proved that the vaccination viruses are safe to target animals and passaging on the target animal does not increase their virulence or produce clinical symptoms of disease. Therefore, it is not necessary to take any special veterinary and animal husbandry actions in respect of the vaccination.

No information is available on the compatibility of this vaccine with any other. Therefore the safety and efficacy of this product when used with any other (either when used on the same day or at different times) has not been demonstrated”.

Do not mix with any other vaccine/ immunological product.


200 doses, 500 doses, 1000 doses, 2 500 doses, 5000 doses

10 x 200 doses, 10 x 500 doses, 10 x 1000 doses, 10 x 2 500 doses, 10 x 5000 doses

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ORNIMIX Clone B1+H120, lyophilizate for the preparation of suspension for chickens (Poultry Vaccines)

Vaccine for active immunization of fowl against Newcastle avian disease and infectious bronchitis of Massachusetts type.

One vaccination dose contains:

  • Active substances:Paramyxovirus pseudopestis avium, strain Bio 52:  NDV B1      min. 106.0 EID50  –  max. 107.5 EID50Virus bronchitidis infectiosae avium, strain Bio 53: IBV H 120 min. 103.0 EID50  –  max. 104.8 EID50Excipients: Nutrimentum pro lyophilisatione


For active immunization of fowl against Newcastle avian disease and infectious bronchitis of Massachusetts type.

For prevention of infection and  mortality caused  by  Newcastle disease virus and by infectious bronchitis virus.

Onset of immunity:

The immunity against Newcastle disease and infectious bronchitis starts not later than 14 and 7 days after primovaccination, respectively, and maternal antibodies have no negative influence on the efficacy of vaccination.

Time of immunity duration:

The immunity lasts for 6 weeks after spray and oculonasal primovaccination and 4 weeks after per oral primovaccination. After revaccination, the immunity persists for 6 weeks as a minimum. The level of immunity against Newcastle disease can be evaluated after revaccination on the basis of serological examination.


Only healthy animals should be vaccinated.

Do not use in animals that are showing signs of  disease

Adverse reactions:

Post-vaccination reactions may occur in particular after unsuitable vaccine application by spraying, because fine micro-droplets (aerosol mist) cause inhalation of the vaccination virus into the lower air passages and respiratory disease as its consequence.

Therapeutic form: Domestic fowl – chickens from the age of one day.

Dosage for each species, rote(s) and method of administration:

Individual oculonasal  application:

The lyophilized vaccine is dissolved in a sterile solvent (e.g. water for injections). The vaccine is applied by a common eye-dropper onto the conjunctiva mucosa or nostril of individual birds; it is necessary to provide breath suction of the droplet by the animal.

Mass spray application:

Distilled water or cool purified water free from chlorine and iron residues is used for vaccine dissolving. The device, specified exclusively for this purpose and generating droplets (diameter of 30 to 100  μm) is used for vaccination. For one day chickens 1000 doses will be dissolved in the 200-250 volume; the sprayer nozzle has to be set to generation of a “coarse spray” = small droplets falling as a fine rain. For older poultry 1000 doses are dissolved in one litre of water and the sprayer nozzle is set to generation of fine droplets. The vaccination solution is sprayed uniformly at the distance of 30 to 50 cm above the adequate number of animals under soft lighting.

Mass application into potable water:

It is recommended to vaccinate the chickens from the 4th day after hatching, when reliable intake of the vaccination dose in potable water can be assumed. The vaccine is administered in the morning, when the poultry is thirsty enough. The vaccine is administered (depending on age) dissolved in such potable water quantity which will be consumed within 2 hours.

Re-vaccination is carried out every six weeks after the first oculonasal or spray administration and in 4 weeks after the first peroral vaccination. Further vaccinations are carried out every six weeks.

In the regions with endemic occurrence of the Newcastle disease re-vaccination should be realized in four-week intervals and the first vaccination shall be carried out oculonasally or by spraying; before egg-laying the inactivated vaccine against Newcastle disease and avian infectious bronchitis should be applied.

Advice on correct administration:

  • Content of antiseptics and disinfectants, presence of chlorine and iron in the water used for vaccine dissolving affects the vaccination virus negatively and has adverse impact on vaccine efficiency.  Virus activity can be potentiated by adding the skimmed cow’s milk – 50 ml and/or powdered milk – 2g/lt of the vaccination solution. The technical device specified for vaccine application, incl. the watering place must be kept clean, free from any detergent and disinfectant residues.Special precautions for use in animalsOnly healthy animals should be vaccinated.Special precautions to be taken by the person administering the veterinary medicinal product to animals

    Avoid exposure to virus during vaccination and use safety goggles and a mask during spray application. Wash and disinfect your hands after the vaccination is finished. Wash used equipment and inactivate the vaccine residues with an efficient disinfectant, or by heat treatment (boiling or burning).

Withdrawal period: Without withdrawal period

Special storage precautions:

  • Keep out of the reach and sight of children.Store in a refrigerator (2 °c – 8 °c)Shelf-life of the veterinary medicinal product in the intact container: 2 year.Shelf-life after first opening: consume immediately

    Shelf-life after dilution: within 3 hours