Shake well the vial before use.
Only clinically healthy animals in a good nutrition condition can be vaccinated. Possible anti-parasitic treatment should be carried out at least 10 days before the vaccination. The vaccinated animals should not be trained or exercised for one week after the vaccination.When diluted, the vaccine shall be used immediately.
At a dry and dark place at a temperature 2-8 oc. Do not freeze!
Do not use after the expiry date stated on the label.When diluted, the vaccine shall be used immediately.
Vaccine against canine distemper, inf. hepatitis, inf. laryngotracheitis, parvovirosis, parainfluenza vivid and leptospirosis and rabies in dogs inactivated.
Composition – 1 ml:
Component DHPPi (freeze-dried):
Virus febris contagiosae canis min. 103.0 TCID50, max.104.5 TCID50
Virus laryngotracheitidis contagiosae canis min. 103.5 TCID50, max.104.5 TCID50
Parvovirus enteritidis canis min. 104.5 TCID50, max.105.5TCID50
Virus parainfluensis canis min. 103.0 TCID50, max.104.2 TCID50
Nutrimentum pro lyophilisatione ad 1 ml
Component LR (solution):
Virus rabiei inactivated min. 2 IU
Leptospira icterohaemorrhagiae inact. min. 1 x 107.0
Leptospira canicola inact. min. 1 x 107.0
Leptospira grippotyphosa inact. min. 1 x 107.0
Nutrimentum ad cultivationem leptospirae
Drug form:Solution for injection
After the application of the vaccine to the animals body, antigens contained in the vaccine are identified as foreign particles and is followed by the activation of protective mechanisms in the organisms (macrophages, opsonins, interleukins, B-lymphocytes etc.), in result of which specific antibodies against antigen determinants contained in the vaccine are formed. These mechanisms should prevent development of the disease in the event of infection.Immunity is starting after 14 days after first vaccination and firm immunity is developed after further 14 days after re-vaccination. The revaccination shall be performed within 14 – 21 days. The revaccination should be repeated every year in order to keep permanent immunity of the animals vaccinated.
For the active immunization of dogs against distemper, infectious hepatitis, infectious laryngotracheitis, parvovirosis, parainfluenza, rabies and the most frequently occurred leptospira serovars (leptospira icterohaemorrhagiae, leptospira canicola, leptospira grippotyphosa) in dogs at the age of 12 weeks and above.
Interaction:The vaccine Biocan DHPPi + LR can be used separately or simultaneously with vaccines Biocan C, Biocan M Plus, Biocan B.
Contraindication: Total pyrexial disease
Administration and dosage: 1 ml irrespective of weight and breed, at the age of 12 weeks and above.
Method of administration:
Local reaction (like a pea in size) can be formed in the vaccine application spot that will disappear on its own accord within 3 weeks.Hypersensitivity can occur only rarely.